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NGEN.EXE errors after Vanguard Systems IMS/21 client install

Anyone familiar with Vanguard Systems IMS/21 client install (version 7.3.0)? Trying to install on devices with the latest version of Windows 10.

I can install quietly and successfully via SCCM, using the command line:

SETUP.EXE /s /f1".\IMS21_response.iss"

Install finishes successfully according to Software Center, as well as Programs and Features on the target device. But near the end of the install,  a DOS window opens and then stays open for at least an hour, maybe longer. Messages in the DOS window are similar to the following:

Microsoft (R) CLR Native Image Generator - Version 4.8.4320.0
Copyright (c) Microsoft Corporation.  All rights reserved.
Failed to load dependency stdole of assembly Microsoft.VisualBasic.Compatibility, Version=10.0.0.0, Culture=neutral, PublicKeyToken=b03f5f7f11d50a3a because of the following error : The system cannot find the file specified. (Exception from HRESULT: 0x80070002)
Failed to load dependency Leadtools.Multimedia of assembly Leadtools.Annotations, Version=17.5.4.0, Culture=neutral, PublicKeyToken=9cf889f53ea9b907 because of the following error : The system cannot find the file specified. (Exception from HRESULT: 0x80070002)
2>    Compiling assembly Accessibility, Version=4.0.0.0, Culture=neutral, PublicKeyToken=b03f5f7f11d50a3a (CLR v4.0.30319) ...
1>    Compiling assembly System, Version=4.0.0.0, Culture=neutral, PublicKeyToken=b77a5c561934e089 (CLR v4.0.30319) ...
2>Error compiling Accessibility, Version=4.0.0.0, Culture=neutral, PublicKeyToken=b03f5f7f11d50a3a: Windows cannot verify the digital signature for this file. A recent hardware or software change might have installed a file that is signed incorrectly or damaged, or that might be malicious software from an unknown source. (Exception from HRESULT: 0x80070241)
2>Ngen failed to generate native code for image Accessibility, Version=4.0.0.0, Culture=neutral, PublicKeyToken=b03f5f7f11d50a3a because of the following error: Windows cannot verify the digital signature for this file. A recent hardware or software change might have installed a file that is signed incorrectly or damaged, or that might be malicious software from an unknown source. (Exception from HRESULT: 0x80070241)
2>Ngen will retry compilation of image Accessibility, Version=4.0.0.0, Culture=neutral, PublicKeyToken=b03f5f7f11d50a3a

Lots of similar failure-related messages, on and on. Only relevant entry I've spotted in Event Viewer is confirmation that the install was successful. Process Monitor doesn't reveal anything helpful in terms of events correlating to the messages I'm seeing from the NGEN window. Stumped as to what the NGEN process is trying to accomplish and how to resolve.

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